Dr. Yamanaka used a retrovirus to insert four genes into a mousecell to return it to a "pluripotent" state-capable of turning intoalmost any kind of cell. Last month a team at Johns HopkinsUniversity and the Sloan-Kettering Institute for Cancer Research,using a version of Dr. Yamanaka's technique, successfully grew nerve cells from a patient suffering froma rare disease called Riley-Day syndrome, which is linked to earlymortality, seizures and other symptoms and caused by a fault in onegene.
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