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MK-3475 was a single arm phase II study enrolling 37 platinum resistant OC patients and aimed at assessing the efficacy of pembrolizumab in combination with weekly paclitaxel: the study reported an ORR of 51.4%, a disease control rate of 86.5%, with 64.5% of patients progression free at 6-month, a median PFS of 7.6 months, and a median OS of 13.4 months [29].




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